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Starting doses on the lower end (300mcg) and progressing slowly makes sense
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Adults aged 18 and up need at least 2.4 micrograms per day
Always start tirzepatide at 2.5 mg weekly, regardless of your prior semaglutide dose
After discontinuation, close monitoring is essential: weight should be checked every 4-8 weeks initially, and for diabetes patients, self-monitoring of blood glucose or continuous glucose monitoring should continue as indicated, with A1C assessment within approximately 3 months of stopping to detect metabolic deterioration early and implement alternative management strategies